Barriers to translating continuous monitoring technologies for preventative medicine

ABSTRACT While treatment remains essential, disease prevention often proves more effective in improving outcomes, enhancing well-being and reducing healthcare costs. Despite this understanding, preventative medical practices are still underutilized. Continuous monitoring technologies can help to address this gap by enabling early symptom detection, tracking disease recurrence and assessing treatment responses, yet few of the technologies have been integrated into clinical practice. In this Review, we discuss notable advances in continuous monitoring and the barriers to their translation. We focus on technologies that enable either continuous measurement for at least one week or periodic measurements for at least one month, including remotely interfacing technologies, wearables and other directly interfacing systems, and internally interfacing implanted devices. Continuous monitoring improves disease-risk assessment, tracks disease progression and enhances overall health management. However, broader and more reliable datasets from diverse clinical trials, alongside supportive policies and financial incentives, will be essential to overcoming translational barriers and to integrating these technologies into healthcare.

Contributors: Jack Chen, Patricia Jastrzebska-Perfect, Peter Chai, Mehmet Girayhan Say, Jiaobing Tu, Wei Gao, Florencia Halperin, Joshua Korzenik, Hen-Wei Huang, Dina Katabi, Giovanni Traverso